Where possible we recommend completing in a single session.
The research, led by QIMR Berghofer Medical Research Institute and Flinders University in Australia, has been published in the international Nature Genetics journal. The research, led by QIMR Berghofer Medical Research Institute and Flinders University, has been published today in the journal Nature Genetics. Researchers have identified 107 genes that increase a person’s risk of developing glaucoma, and they have developed a genetic test to detect those at risk of going blind from it. The research, led by QIMR Berghofer Medical Research Institute and Flinders University, has been published today in the journal Nature Genetics.

This would have benefits for patients, doctors and the health care system with reduced interventions and reduced costs.”Australians interested in taking part in the research can visit the Genetics of Glaucoma study website The research has been funded by the National Health and Medical Research Council.About 300,000 Australians have glaucoma, according to the peak support organisation Glaucoma Australia.About three per cent of the population will develop glaucoma by the age of 65 (one in 30 people).Chair and Academic Head of Ophthalmology at Flinders University, Professor Jamie CraigChair and Academic Head of Ophthalmology at Flinders University, Professor Jamie CraigMedia contact details for this story are only visible to registered journalists.


Not everyone with a high glaucoma genetic risk score will get the disease. The only identifier participant's data will have is a linkage ID. What are the risk factors?I’m worried about my glaucoma risk, what should I do?You’ve published a genetic predictor of glaucoma risk – can it tell me if I will get glaucoma?When will your genetic predictor of risk be available?You already have a genetic predictor of glaucoma risk - why do you need to do more work on this topic?I have provided a saliva sample but the sample is discoloured:I don’t have a copy of the saliva sample collection instructions:Aboriginal and Torres Strait Islander Health Research TraineeshipView Participant Information - Genetics of Glaucoma Study

Glaucoma is one of the most strongly genetic human diseases. In a very small proportion of people, glaucoma can arise as result of steroid treatment – if you are concerned about this ask your doctor.Whilst having a family history of the disease increases your risk, family history alone is not a clear predictor of your own risk. This will allow them to take preventative measures, which could be as easy as providing a saliva sample to complete the predictive test.The next phase of Associate Professor MacGregor’s research will involve recruitment, where he is seeking people with glaucoma and people with a family history of glaucoma to participate.‘We are hoping a significant number of the 300 000 current sufferers come forward to participate in the study. From: QIMR Berghofer Medical Research Institute Australian researchers have identified 107 genes that increase a person’s risk of developing the eye disease glaucoma, and developed a genetic test to detect those at risk of going blind from it. Rather, the test provides a quantitative measure of your glaucoma risk. "The researchers are now hoping to recruit 20,000 people with a personal or family history of the disease to join their Genetics of Glaucoma Study so that they can identify more genes that play a role in the condition.“We want to know who will get glaucoma, and for those who are susceptible, we want to be able to pinpoint at what age they’re going to get it,” Associate Professor MacGregor said.“That would allow us to develop a personalised approach for earlier treatment of high-risk individuals, and means people at lower risk could have less intensive monitoring and treatment.

Glaucoma is an age-related disease; a person’s chance of developing glaucoma significantly increases after the age of 50. Please return it to us and if we need you to provide another sample we will be in contact.Please find instructions on how to provide a saliva sample into the tube Receive the latest news from QIMR Berghofer, including: medical research updates, information about diseases and disorders, Q&As with our scientists, upcoming events and community fundraiser news.Copyright © 2020 QIMR Berghofer Medical Research InstituteCan I read the Participant Information Sheet before I agree to take part?How will you use the survey, biological and genetic information data I give you?How is the information I give you kept confidential?Do I have to disclose my participation to my life insurer?How likely am I to get glaucoma?

This is hugely exciting because, if a person is aware of the predicted age when they may develop glaucoma, they can take preventative treatments in the early stages.‘If we can identify who is most at risk of developing glaucoma at the earliest opportunity, we can make sure those individuals receive the preventative treatment they need to stop them from going blind as they age.‘Early treatment is vital because, once a person experiences vision loss, it is impossible to reverse,’ Associate Professor MacGregor said.Glaucoma is treatable with eye drops or surgery, depending on the amount of damage sustained by the optic nerve but, if left untreated, the damage is irreversible. Internal access to these databases and samples are compartmentalised - the data collection team can only access your personal and survey information, analysts can only access your survey information and genetic data, and laboratory staff can only access your biosample and DNA [the latter two groups only have your ID number]. This will enable us to further refine the genetic predictive test, making it even more accurate,’ Associate Professor MacGregor said.Receive the latest news from QIMR Berghofer, including: medical research updates, information about diseases and disorders, Q&As with our scientists, upcoming events and community fundraiser news.Copyright © 2020 QIMR Berghofer Medical Research InstituteAboriginal and Torres Strait Islander Health Research Traineeship However, researchers will be providing everyone who participates with a newsletter. This should typically take around 10 minutes to complete. QIMR Berghofer Medical Research Institute


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